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1

Sparse-CAPR: Highly accelerated 4D CE-MRA with parallel imaging and nonconvex compressive sensing

Joshua D. Trzasko, Clifton R. Haider, Eric A. Borisch, Norbert G. Campeau, James F. Glockner, Stephen J. Riederer, Armando Manduca

Journal:

Magnetic Resonance in Medicine

Year:

2011

Language:

english

File:

PDF, 678 KB

english, 2011

2

A High-Throughput Fluorescent Polarization Assay for Nuclear Receptor Binding Utilizing Crude Receptor Extract

Siqi Lin, Cindy L. Bock, Debra B. Gardner, Jeffery C. Webster, Margaret F. Favata, James M. Trzaskos, Kevin R. Oldenburg

Journal:

Analytical Biochemistry

Year:

2002

Language:

english

File:

PDF, 132 KB

english, 2002

3

Analysis of sterols and other biologically significant steroids: Edited by W. David Nes and Edward J. Parish. Academic Press, San Diego, CA, 1989. 341 pp. $69.00. Dedicated to William R. Nes 1926–1988

Robert T. Fischer, James M. Trzaskos

Journal:

Analytical Biochemistry

Year:

1989

Language:

english

File:

PDF, 148 KB

english, 1989

4

Rational design, synthesis and structure–Activity relationships of a cyclic succinate series of TNF-α converting enzyme inhibitors. Part 1: lead identification

Chu-Biao Xue, Xiaohua He, John Roderick, Ronald L. Corbett, James J.-W. Duan, Rui-Qin Liu, Maryanne B. Covington, Robert C. Newton, James M. Trzaskos, Ronald L. Magolda, Ruth R. Wexler, Carl P. Decicc

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

5

Synthesis and structure–activity relationship of a novel sulfone series of TNF-α converting enzyme inhibitors

Chu-Biao Xue, Xiao-Tao Chen, Xiaohua He, John Roderick, Ronald L. Corbett, Bahman Ghavimi, Rui-Qin Liu, Maryanne B. Covington, Mingxin Qian, Maria D. Ribadeneira, Krishna Vaddi, James Trzaskos, Robert

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 310 KB

english, 2004

6

N-Arylalkylpiperidine urea derivatives as CC chemokine receptor-3 (CCR3) antagonists

Douglas G. Batt, Gregory C. Houghton, John Roderick, Joseph B. Santella III, Dean A. Wacker, Patricia K. Welch, Yevgeniya I. Orlovsky, Eric A. Wadman, James M. Trzaskos, Paul Davies, Carl P. Decicco,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 278 KB

english, 2005

7

Synthesis and structure–activity relationship of a novel, achiral series of TNF-α converting enzyme inhibitors

John L. Gilmore, Bryan W. King, Cathy Harris, Thomas Maduskuie, Stephen E. Mercer, Rui-Qin Liu, Maryanne B. Covington, Mingxin Qian, Maria D. Ribadeneria, Krishna Vaddi, James M. Trzaskos, Robert C. N

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

8

Discovery of β-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors

James J.-W. Duan, Lihua Chen, Zhonghui Lu, Chu-Biao Xue, Rui-Qin Liu, Maryanne B. Covington, Mingxin Qian, Zelda R. Wasserman, Krishna Vaddi, David D. Christ, James M. Trzaskos, Robert C. Newton, Carl

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 268 KB

english, 2008

9

α,β-Cyclic-β-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE)

Gregory R. Ott, Naoyuki Asakawa, Rui-Qin Liu, Maryanne B. Covington, Mingxin Qian, Krishna Vaddi, Robert C. Newton, James M. Trzaskos, David D. Christ, Laurine Galya, Thomas Scholz, Will Marshall, Jam

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 242 KB

english, 2008

10

Potent, exceptionally selective, orally bioavailable inhibitors of TNF-α Converting Enzyme (TACE): Novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1′ substituents

Gregory R. Ott, Naoyuki Asakawa, Zhonghui Lu, Rajan Anand, Rui-Qin Liu, Maryanne B. Covington, Krishna Vaddi, Mingxin Qian, Robert C. Newton, David D. Christ, James M. Trzaskos, James J.-W. Duan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

11

Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE): Discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1′ substituents

Zhonghui Lu, Gregory R. Ott, Rajan Anand, Rui-Qin Liu, Maryanne B. Covington, Krishna Vaddi, Mingxin Qian, Robert C. Newton, David D. Christ, James Trzaskos, James J.-W. Duan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

12

Benzothiazole based inhibitors of p38α MAP kinase

Chunjian Liu, James Lin, Sidney Pitt, Rosemary F. Zhang, John S. Sack, Susan E. Kiefer, Kevin Kish, Arthur M. Doweyko, Hongjian Zhang, Punit H. Marathe, James Trzaskos, Murray Mckinnon, John H. Dodd,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 202 KB

english, 2008

13

A microplate assay specific for the enzyme aggrecanase

Jeffery A Miller, Rui-Qin Liu, Gary L Davis, Michael A Pratta, James M Trzaskos, Robert A Copeland

Journal:

Analytical Biochemistry

Year:

2003

Language:

english

File:

PDF, 190 KB

english, 2003

14

COX-3: in the wrong frame in mind

Joseph E. Dinchuk, Richard Q. Liu, James M. Trzaskos

Journal:

Immunology Letters

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

15

Chemistry and pharmacokinetics of diarylthiophenes and terphenyls as selective COX-2 inhibitors

Donald J.P. Pinto, Robert A. Copeland, Maryanne B. Covington, William J. Pitts, Douglas G. Batt, Michael J. Orwat, Gilbert N. Lam, Amita Joshi, Yuk-Charn Chan, Shuaige Wang, James M. Trzaskos, Ronald

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 330 KB

english, 1996

16

COMPARISON OF SNAKE VENOM REPROLYSIN AND MATRIX METALLOPROTEINASES AS MODELS OF TNF-α CONVERTING ENZYME

Drew E Van Dyk, Petra Marchand, Robert C Bruckner, Jay W Fox, Bruce D Jaffee, Paul L Gunyuzlu, Gary L Davis, Sherrill Nurnberg, Maryanne Covington, Carl P Decicco, James M Trzaskos, Ronald L Magolda,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 806 KB

english, 1997

17

Extracellular signal-regulated kinase-dependent interstitial macrophage proliferation in the obstructed mouse kidney

YINGJIE HAN, TAKAO MASAKI, LYNETTE A HURST, YOHEI IKEZUMI, JAMES M TRZASKOS, ROBERT C ATKINS, DAVID J NIKOLIC-PATERSON

Journal:

Year:

2008

Language:

english

File:

PDF, 675 KB

english, 2008

18

Aggrecanase: A Target for the Design of Inhibitors of Cartilage Degradation

ELIZABETH C. ARNER, MICHAEL A. PRATTA, CARL P. DECICCO, CHU-BIAO XUE, ROBERT C. NEWTON, JAMES M. TRZASKOS, RONALD L. MAGOLDA, MICKY D. TORTERELLA

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.06 MB

english, 1999

19

10.1038/2836

Sweatt, J. David, Atkins, Coleen M., Selcher, Joel C., Petraitis, Joseph J., Trzaskos, James M.

Journal:

Nature Neuroscience

Year:

1998

Language:

english

File:

PDF, 216 KB

english, 1998

20

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Dual-Action Inhibitors of Cholesterol Biosynthesis

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.45 MB

english, 1992

21

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Natural Rubber Biosynthesis

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 918 KB

english, 1992

22

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Inhibition of Sterol Metabolism in Insects and Nematodes

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.55 MB

english, 1992

23

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || 2,3-Oxidosqualene Cyclase and Squalene Epoxidase as Target Enzymes for the Development of New Sterol Biosynthesis Inhibitors

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.35 MB

english, 1992

24

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Regulation of Monoterpene Biosynthesis in Conifer Defense

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.58 MB

english, 1992

25

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Regulation of Sterol Biosynthesis and Its Phylogenetic Implications

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 3.32 MB

english, 1992

26

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Production of Natural Carotenoids

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.03 MB

english, 1992

27

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Isoprenylation of Low Molecular Mass Guanine Nucleotide-Binding Proteins in Mammalian Cells

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.71 MB

english, 1992

28

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Enzyme Systems

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.22 MB

english, 1992

29

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Oxysterol Regulation of Cholesterol Biosynthesis

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.37 MB

english, 1992

30

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Role of Sphingomyelin in Cellular Cholesterol Homeostasis

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 743 KB

english, 1992

31

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Cytochrome P450-Dependent 14α-Demethylase

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.32 MB

english, 1992

32

[ACS Symposium Series] Regulation of Isopentenoid Metabolism Volume 497 || Squalene Epoxidase Inhibitors

Nes, W. David, Parish, Edward J., Trzaskos, James M.

Year:

1992

Language:

english

File:

PDF, 1.05 MB

english, 1992

33

Effects of 15-Oxa-32-vinyl-lanost-8-ene-3β,32 diol on the Expression of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Low Density Lipoprotein Receptor in Rat Liver

Gene C. Ness, Dayami Lopez, Christopher M. Chambers, Zhihong Zhao, Deborah L. Beach, Soo S. Ko, James M. Trzaskos

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 247 KB

english, 1998

34

Inhibition of MAP Kinase Kinase (MEK) Results in an Anti-inflammatory Response in Vivo

Bruce D. Jaffee, Elizabeth J. Manos, Robert J. Collins, Phillip M. Czerniak, Margaret F. Favata, Ronald L. Magolda, Peggy A. Scherle, James M. Trzaskos

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 78 KB

english, 2000

35

Differential Regulation of IL-1β and TNF-α RNA Expression by MEK1 Inhibitor after Focal Cerebral Ischemia in Mice

Hugh Wang, Lin Xu, Sivakami Venkatachalam, James M. Trzaskos, Steven M. Friedman, Giora Z. Feuerstein, Xinkang Wang

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 83 KB

english, 2001

36

Expression Purification and Characterization of Recombinant Human Inducible Prostaglandin G/H Synthase from Baculovirus-Infected Insect Cells

Henry J. George, Drew E. Van Dyk, Rose A. Straney, James M. Trzaskos, Robert A. Copeland

Journal:

Protein Expression and Purification

Year:

1996

Language:

english

File:

PDF, 127 KB

english, 1996

37

Cytosolic modulators of activities of microsomal enzymes of cholesterol biosynthesis purification and characterization of a non-specific lipid-transfer protein

James M. Trzaskos, James L. Gaylor

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1983

Language:

english

File:

PDF, 1.41 MB

english, 1983

38

Cholesterol biosynthesis from lanosterol: regulation and purification of rat hepatic sterol 14-reductase

Chap-Ki Kim, Kye-Im Jeon, Dong-Min Lim, Tae-Neung Johng, James M. Trzaskos, James L. Gaylor, Young-Ki Paik

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1995

Language:

english

File:

PDF, 874 KB

english, 1995

39

Sterol-mediated suppression of HMG-CoA reductase mRNA levels in cultured cells requires protein synthesis

James M. Trzaskos, Marketa Jonas, Harry W. Chen

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 341 KB

english, 1989

40

Identification of lanosterol 14α-methyl demethylase in human tissues

Judy L. Raucy, Susan J. Carpenter, James M. Trzaskos

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 638 KB

english, 1991

41

Receptor density dictates the behavior of a subset of steroid ligands in glucocorticoid receptor-mediated transrepression

Qihong Zhao, Jian Pang, Margaret F. Favata, James M. Trzaskos

Journal:

International Immunopharmacology

Year:

2003

Language:

english

File:

PDF, 900 KB

english, 2003

42

Multiple Female Reproductive Failures in Cyclooxygenase 2–Deficient Mice

Hyunjung Lim, Bibhash C Paria, Sanjoy K Das, Joseph E Dinchuk, Robert Langenbach, James M Trzaskos, Sudhansu K Dey

Journal:

Year:

1997

Language:

english

File:

PDF, 4.09 MB

english, 1997

43

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph E Dinchuk, Stacia L Kargman, Hiroko Oshima, Bruno Hancock, Elizabeth Kwong, James M Trzaskos, Jilly F Evans, Makoto M Taketo

Journal:

Year:

1996

Language:

english

File:

PDF, 1000 KB

english, 1996

44

Recombinant Human 92-kDa Type IV Collagenase/Gelatinase from Baculovirus-Infected Insect Cells: Expression, Purification, and Characterization

Henry J. George, Petra Marchand, Kathleen Murphy, Barbara H. Wiswall, Randine Dowling, John Giannaras, Gregory F. Hollis, James M. Trzaskos, Robert A. Copeland

Journal:

Protein Expression and Purification

Year:

1997

Language:

english

File:

PDF, 377 KB

english, 1997

45

Discovery of Macrocyclic Hydroxamic Acids Containing Biphenylmethyl Derivatives at P1‘, a Series of Selective TNF-α Converting Enzyme Inhibitors with Potent Cellular Activity in the Inhibition of TNF-α Release

Xue, Chu-Biao, He, Xiaohua, Corbett, Ronald L., Roderick, John, Wasserman, Zelda R., Liu, Rui-Qin, Jaffee, Bruce D., Covington, Maryanne B., Qian, Mingxin, Trzaskos, James M., Newton, Robert C., Magol

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 159 KB

english, 2001

46

Role of the ERK pathway in psychostimulant-induced locomotor sensitization

Emmanuel Valjent, Jean-Christophe Corvol, James M Trzaskos, Jean-Antoine Girault, Denis Hervé

Journal:

BMC Neuroscience

Year:

2006

Language:

english

File:

PDF, 646 KB

english, 2006

47

Co-stimulatory molecules as therapeutic targets in allergic airways disease

Suzanne J. Suchard, James Trzaskos, Steven G. Nadler, Murray J. McKinnon

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2007

Language:

english

File:

PDF, 814 KB

english, 2007

48

Sultam Hydroxamates as Novel Matrix Metalloproteinase Inhibitors

Cherney, Robert J., Mo, Ruowei, Meyer, Dayton T., Hardman, Karl D., Liu, Rui-Qin, Covington, Maryanne B., Qian, Mingxin, Wasserman, Zelda R., Christ, David D., Trzaskos, James M., Newton, Robert C., D

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 91 KB

english, 2004

49

Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties

Trzaskos, James M., Ko, Soo S., Magolda, Ronald L., Favata, Margaret F., Fischer, Robert T., Stam, Simon H., Johnson, Paul R., Gaylor, James L.

Journal:

Year:

1995

Language:

english

File:

PDF, 905 KB

english, 1995

50

Antiinflammatory 4,5-Diarylpyrroles. 2. Activity as a Function of Cyclooxygenase-2 Inhibition

Wilkerson, Wendell Wilkie, Copeland, Robert A., Covington, Maryanne, Trzaskos, James M.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 805 KB

english, 1995

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